2-Methylsulfonyl-1,2,4-triazolo[1,5-a]quinazolin-5(4H)-one
نویسندگان
چکیده
The triazoloquinazoline fused-ring system of the title compound, C(10)H(8)N(4)O(3)S, is essentially planar (r.m.s. deviation = 0.027 Å). In the crystal, adjacent mol-ecules are linked by N-H⋯O(sulfon-yl) hydrogen bonds, generating a helical chain running along the b axis.
منابع مشابه
2-Benzyloxy-1,2,4-triazolo[1,5-a]quinazolin-5(4H)-one. Corrigendum
The name of one of the authors in the paper by Al-Salahi et al. [Acta Cryst. (2011), E67, o1861] is corrected.[This corrects the article DOI: 10.1107/S1600536811024962.].
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In the present study a series of 1-substituted-4-(2-methoxyphenyl)-s-triazolo[4,3-a]quinazolin-5(4H)-ones were synthesized and are screened for their H1-antihistaminic activity. The synthesized compounds were characterized by IR, H-NMR and mass spectral data; the purity of the compounds was determined by elemental analysis. Antihistaminic activity of the title compounds was evaluated by histami...
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عنوان ژورنال:
دوره 68 شماره
صفحات -
تاریخ انتشار 2012